Vacuum drying characteristics of the production of the tablet
Drying is a tablet production from raw material extraction to semi- dry paste last link . Drying equipment and technology directly related to product quality. In tablet production, control , no matter how the other links , if there appears to uneven drying in the drying , the active ingredient is destroyed , thermal deterioration and other problems , the quality of the tablet will eventually fall short.
Vacuum drying equipment and technology as a low-temperature drying , the active ingredient less damage , loose and easy to dissolve absorption , drying and sterilization at the same time the advantages of active ingredient which can ensure the high , sterile indicators of high oral absorption . Therefore, with the current common oven drying , spray drying method compared continuous vacuum drying method has many unique advantages , to ensure product quality is much higher than other drying methods used products .
Vacuum drying method has the following main features: low-temperature drying in a vacuum environment, the lower the boiling point of water , can achieve low-temperature drying for drying heat sensitive materials provided favorable conditions can be better to avoid the effective ingredients in the drying process is heat damage . Production of natural products such as extracts , the product in the drying process in a vacuum , closed environment , mild drying process (temperature 40 ℃ ~ 60 ℃), can maximize maintain its active ingredient.
Differentiation oxygen under vacuum oxygen pressure , the material in the drying process to avoid the oxidation deterioration phenomenon , to protect the quality of the product to be dried . Microporous loose state in a high vacuum , the product after a period of time to gradually After drying, the internal porous microstructure point directly to the desired particle size of grinding , the particle flow is very good.
Meanwhile , because of its loose structure of microscopic particles of excellent instant , more conducive to the body to absorb . Synchronization sterilization in a vacuum hypoxia, can effectively inhibit the reproduction of bacteria to kill bacteria purposes. In the dry product , while also sterilization functions again achieved . Double sterilization, to ensure product sterility standards.